Biodegradable Toothbrushes. Handles made from non-GMO corn starch. Soft nylon bristles. BPA free. Biodegradable packaging. Directions: Use minimum pressure and brush in a circular motion. Use with The Natural Family Co. toothpaste. Replace toothbrush every 6-8 weeks or earlier if worn. Replace after illness. Rinse thoroughly before & after use. Allow bristles to air dry. Sterilize often.